clonazepam

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Literature

The publications shown below are associated with this chemical in PharmGKB based on (1) literature annotations, (2) variant annotations, (3) VIP summaries, or (4) pathways.

    19 items
    Literature
    Use of pharmacogenetics for benzodiazepine prescription: state of the art and expectations.
    Pharmacogenomics. 2022. Zubiaur Pablo and Abad-Santos Francisco.
    PGx Paper Type: Implementation, Editorial
    Literature
    Serum protein binding of 25 antiepileptic drugs in a routine clinical setting: A comparison of free non-protein-bound concentrations.
    Epilepsia. 2017. Patsalos Philip N, Zugman Miguel, Lake Charlotte, James Anthony, Ratnaraj Neville and Sander Josemir W.
    Literature
    Clinical Impact of Pharmacogenetic-Guided Treatment for Patients Exhibiting Neuropsychiatric Disorders: A Randomized Controlled Trial.
    The primary care companion for CNS disorders. 2017. Olson Marilyn C, Maciel Alejandra, Gariepy Jean Francois, Cullors Ali, Saldivar Juan-Sebastian, Taylor David, Centeno Joel, Garces Jorge A and Vaishnavi Sandeep.
    Literature
    Effectiveness of antiepileptic therapy in patients with PCDH19 mutations.
    Seizure. 2016. Lotte Jan, Bast Thomas, Borusiak Peter, Coppola Antonietta, Cross J Helen, Dimova Petia, Fogarasi Andras, Graneß Irene, Guerrini Renzo, Hjalgrim Helle, Keimer Reinhard, Korff Christian M, Kurlemann Gerhard, Leiz Steffen, Linder-Lucht Michaela, Loddenkemper Tobias, Makowski Christine, Mühe Christian, Nicolai Joost, Nikanorova Marina, Pellacani Simona, Philip Sunny, Ruf Susanne, Sánchez Fernández Iván, Schlachter Kurt, Striano Pasquale, Sukhudyan Biayna, Valcheva Deyana, Vermeulen R Jeroen, Weisbrod Tanja, Wilken Bernd, Wolf Philipp and Kluger Gerhard.
    Pediatric
    Literature
    Clobazam and its active metabolite N-desmethylclobazam display significantly greater affinities for alpha₂- versus alpha₁-GABA(A)-receptor complexes.
    PloS one. 2014. Jensen Henrik Sindal, Nichol Kathryn, Lee Deborah and Ebert Bjarke.
    Literature
    Gene-wide tagging study of the association between ABCC2, ABCC5 and ABCG2 genetic polymorphisms and multidrug resistance in epilepsy.
    Pharmacogenomics. 2011. Kwan Patrick, Wong Virginia, Ng Ping Wing, Lui Colin Hiu Tung, Sin Ngai Chuen, Wong Ka Sing and Baum Larry.
    Pediatric
    Literature
    Interactions between modulators of the GABA(A) receptor: Stiripentol and benzodiazepines.
    European journal of pharmacology. 2011. Fisher Janet L.
    Literature
    Gene-wide tagging study of association between ABCB1 polymorphisms and multidrug resistance in epilepsy in Han Chinese.
    Pharmacogenomics. 2009. Kwan Patrick, Wong Virginia, Ng Ping Wing, Lui Colin Hiu Tung, Sin Ngai Chuen, Poon Wai Sang, Ng Ho Keung, Wong Ka Sing and Baum Larry.
    Pediatric
    Literature
    Effect of common NAT2 variant alleles in the acetylation of the major clonazepam metabolite, 7-aminoclonazepam.
    Drug metabolism letters. 2007. Olivera M, Martínez C, Gervasini G, Carrillo J A, Ramos S, Benítez J, García-Martin E and Agúndez J A G.
    Literature
    ABCB1 polymorphisms influence the response to antiepileptic drugs in Japanese epilepsy patients.
    Pharmacogenomics. 2006. Seo Takayuki, Ishitsu Takateru, Ueda Nao, Nakada Naoyuki, Yurube Keigo, Ueda Kentaro and Nakagawa Kazuko.
    Pediatric
    Literature
    The benzodiazepine site of the GABAA receptor: an old target with new potential?
    Sleep medicine. 2004. Bateson Alan N.
    Literature
    Mapping of the benzodiazepine recognition site on GABA(A) receptors.
    Current topics in medicinal chemistry. 2002. Sigel Erwin.
    Literature
    New insights into the role of the GABA(A)-benzodiazepine receptor in psychiatric disorder.
    The British journal of psychiatry : the journal of mental science. 2001. Nutt D J and Malizia A L.
    Literature
    Inhibition of human hepatic cytochrome P4502E1 by azole antifungals, CNS-active drugs and non-steroidal anti-inflammatory agents.
    Xenobiotica; the fate of foreign compounds in biological systems. 1998. Tassaneeyakul W, Birkett D J and Miners J O.
    Literature
    The benzodiazepine binding site of GABAA receptors.
    Trends in pharmacological sciences. 1997. Sigel E and Buhr A.
    Literature
    Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors.
    Drug metabolism reviews. 1997. Rendic S and Di Carlo F J.
    Literature
    N-acetylation pharmacogenetics.
    Pharmacological reviews. 1985. Weber W W and Hein D W.
    Literature
    Clonazepam acetylation in fast and slow acetylators.
    Clinical pharmacology and therapeutics. 1981. Miller M E, Garland W A, Min B H, Ludwick B T, Ballard R H and Levy R H.
    Literature
    Influence of phenytoin and phenobarbital on the disposition of a single oral dose of clonazepam.
    Clinical pharmacology and therapeutics. 1980. Khoo K C, Mendels J, Rothbart M, Garland W A, Colburn W A, Min B H, Lucek R, Carbone J J, Boxenbaum H G and Kaplan S A.