MTTP

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Pathways

Pathway
In Progress: Lipid modifying agents Pathway, Pharmacodynamics
Cardiovascular and hematology agents
Representation of the candidate genes involved in the mechanism of action of lipid modifying agents alirocumab, evolocumab, inclisiran, lomitapide and evinacumab, indicated for treatment of familial hypercholesterolema.
In Progress: Lipid modifying agents Pathway, Pharmacodynamics diagram
Pathway
Statin Pathway, Pharmacodynamics
Cardiovascular and hematology agents
Genes involved in mediating statin effects on hepatic cholesterol metabolism and consequent effects on plasma lipoprotein transport.
Statin Pathway, Pharmacodynamics diagram