LEP

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Literature

The publications shown below are associated with this gene in PharmGKB based on (1) literature annotations, (2) variant annotations, (3) VIP summaries, or (4) pathways.

    24 items
    Literature
    Genetic risk score for gestational weight gain.
    European journal of obstetrics, gynecology, and reproductive biology. 2024. Mikołajczyk-Stecyna Joanna, Zuk Ewelina, Seremak-Mrozikiewicz Agnieszka, Kurzawińska Grażyna, Wolski Hubert, Drews Krzysztof and Chmurzynska Agata.
    Literature
    Leptin and Leptin Receptor Polymorphisms in Infants and Their Parents: Correlation with Preterm Birth.
    Genes. 2024. Savino Francesco, Sardo Allegra, Gambarino Stefano, Dini Maddalena, Clemente Anna, Pau Anna, Galliano Ilaria and Bergallo Massimiliano.
    Pediatric
    Literature
    Review of pharmacogenomics of psychiatric comorbidities in autism spectrum disorder.
    Pharmacogenomics. 2023. Alvarez Aida, Bote Valentin, Lamborena Cristina, Medina Raquel, Serra-LLovich Alexandre, Hervas Amaia and Arranz Maria J.
    PGx Paper Type: Review
    Literature
    Pharmacogenomics of response to statin treatment and susceptibility to statin-induced adverse drug reactions in Asians: a scoping review.
    Asian biomedicine : research, reviews and news. 2023. Yow Hui-Yin, Hamzah Sharina, Abdul Rahim Nusaibah and Suppiah Vijayaprakash.
    PGx Paper Type: Population Frequency, Review, Uses PharmGKB
    Literature
    Drugs@FDA: Drug Product Myalept (metreleptin), Amryt Pharmaceuticals DAC - BLA125390/SUPPL-24, 02/28/2022
    2022.
    Literature
    Pharmacogenetics of Antipsychotic Treatment in Schizophrenia.
    Methods in molecular biology (Clifton, N.J.). 2022. Elsheikh Samar S M, Müller Daniel J and Pouget Jennie G.
    PGx Paper Type: Implementation, Review, Methods
    Literature
    The pharmacogenetics of treatment with olanzapine.
    Pharmacogenomics. 2021. Zubiaur Pablo, Soria-Chacartegui Paula, Villapalos-García Gonzalo, Gordillo-Perdomo Juan J and Abad-Santos Francisco.
    PGx Paper Type: Review, Uses PharmGKB
    Literature
    Genetic polymorphisms of HTR2C, LEP and LEPR on metabolic syndromes in patients treated with atypical antipsychotic drugs.
    The Journal of pharmacy and pharmacology. 2018. Puangpetch Apichaya, Unaharassamee Weerapon, Jiratjintana Napa, Koomdee Napatrupron and Sukasem Chonlaphat.
    Literature
    Pharmacogenomics of autism spectrum disorder.
    Pharmacogenomics. 2017. Brown Jacob T, Eum Seenae, Cook Edwin H and Bishop Jeffrey R.
    Literature
    Adiponectin and leptin gene polymorphisms in patients with post-transplant diabetes mellitus.
    Pharmacogenomics. 2015. Romanowski Maciej, Dziedziejko Violetta, Maciejewska-Karlowska Agnieszka, Sawczuk Marek, Safranow Krzysztof, Domanski Leszek and Pawlik Andrzej.
    Literature
    Metabolic side effects and pharmacogenetics of second-generation antipsychotics in children.
    Pharmacogenomics. 2015. Devlin Angela M and Panagiotopoulos Constadina.
    Pediatric
    Literature
    Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies.
    Translational psychiatry. 2013. Nurmi E L, Spilman S L, Whelan F, Scahill L L, Aman M G, McDougle C J, Arnold L E, Handen B, Johnson C, Sukhodolsky D G, Posey D J, Lecavalier L, Stigler K A, Ritz L, Tierney E, Vitiello B, McCracken J T and Research Units on Pediatric Psychopharmacology Autism Network.
    Pediatric
    Literature
    Pharmacogenetic testing to predict antipsychotic-induced weight gain: a systematic review.
    Pharmacogenomics. 2011. Risselada Arne J, Mulder Hans, Heerdink Eibert R and Egberts Toine C G.
    Literature
    Polymorphisms of the LEP, LEPR and HTR2C gene: obesity and BMI change in patients using antipsychotic medication in a naturalistic setting.
    Pharmacogenomics. 2011. Gregoor Jochem G, van der Weide Jan, Loovers Harriët M, van Megen Harold J G M, Egberts Toine C G and Heerdink Eibert R.
    Pediatric
    Literature
    The modulating effect of the androgen receptor on craving in alcohol withdrawal of men is partially mediated by leptin.
    The pharmacogenomics journal. 2010. Lenz B, Frieling H, Jacob C, Heberlein A, Kornhuber J, Bleich S and Hillemacher T.
    Literature
    Leptin gene -2548G/A variants predict risperidone-associated weight gain in children and adolescents.
    Psychiatric genetics. 2009. Calarge Chadi A, Ellingrod Vicki L, Zimmerman Bridget, Acion Laura, Sivitz William I and Schlechte Janet A.
    Pediatric
    Literature
    Genetic associations with thalidomide mediated venous thrombotic events in myeloma identified using targeted genotyping.
    Blood. 2008. Johnson David C, Corthals Sophie, Ramos Christine, Hoering Antje, Cocks Kim, Dickens Nicholas J, Haessler Jeff, Goldschmidt Harmut, Child J Anthony, Bell Sue E, Jackson Graham, Baris Dalsu, Rajkumar S Vincent, Davies Faith E, Durie Brian G M, Crowley John, Sonneveld Pieter, Van Ness Brian and Morgan Gareth J.
    Literature
    Genetic correlates of olanzapine-induced weight gain in schizophrenia subjects from north India: role of metabolic pathway genes.
    Pharmacogenomics. 2008. Srivastava Vibhuti, Deshpande Smita N, Nimgaonkar Vishwajit L, Lerer Bernard and Thelma Bk.
    Literature
    Estimating coverage and power for genetic association studies using near-complete variation data.
    Nature genetics. 2008. Bhangale Tushar R, Rieder Mark J and Nickerson Deborah A.
    Literature
    Influence of 5-HT2C receptor and leptin gene polymorphisms, smoking and drug treatment on metabolic disturbances in patients with schizophrenia.
    The British journal of psychiatry : the journal of mental science. 2008. Yevtushenko Olga O, Cooper Stephen J, O'Neill Ryan, Doherty Jennifer K, Woodside Jayne V and Reynolds Gavin P.
    Literature
    The genetics of human obesity.
    Nature reviews. Genetics. 2005. Bell Christopher G, Walley Andrew J and Froguel Philippe.
    Literature
    Drugs@FDA:Drug MYALEPT (Metreleptin) BLA125390
    Literature
    Drugs@HCSC: Drug Product MYALEPTA (metreleptin), Amryt Pharmaceuticals DAC
    Literature
    Metreleptin | European Medicines Agency